Name: Wei Yang
Academic Title: Professor
Email: yangwei1976@suda.edu.cn
Address: Medical Building 402-2212, North District of Dushu Lake Campus
Contact Phone: +86 512 65880065
Ⅰ、Educational and Professional Experience
1、Educational Background:
2000.09-2005.07 Jilin University, School of Public Health, Doctor of Radiation Medicine
1993.09-1998.07 Bethune Medical University, Jilin, Bachelor of Clinical Medicine
2、Professional Experience:
2018.07-Present Soochow University, School of Radiation Medicine and Protection, Professor
2008.09-2018.06 Soochow University, School of Radiation Medicine and Protection, Associate Professor
2005.09-2008.08 Jilin University, School of Public Health,Lecturer
Ⅱ、Research Focus
1、Radiosensitization of hypoxic tumor cells/tumor stem cells
2、Regulatory mechanisms of immunogenic cell death induced by ionizing radiation in tumors
Ⅲ、Project/Honor/Award
1、NSFC, Ionizing radiation-induced immunogenic cell death of glioma stem cells activates CAR-T cell immunotherapy for glioma, 32171234, ￥580,000, 2022.01-2025.12.
2、NSFC, The regulatory effect and mechanism of the cZNF292/SOX9/β-catenin signaling pathway on the radiosensitivity of hypoxic tumor cells, 31870844, ￥550,000, 2019.01-2022.12.
3、NSFC, The regulatory effect and mechanism of the miR-153/Nrf-2/GPx1 signaling pathway on the stemness and radiosensitivity of glioma stem cells through ROS, 31570851, ￥600,000, 2022.01-2025.12.
4、NSFC,Study on the Effect and Mechanism of microRNA-210 on the radiosensitivity of Hypoxic Tumor cells, 81071958, ￥310,000, 2011.01-2013.12.
5、NSFC, Experimental study on the Enhancement of tumor radiotherapy effect by Small interfering RNA targeting hypoxia-inducible factor-1 and surviving genes, 30600160, ￥230,000, 2007.01-2009.12.
Ⅳ、Academic Part-time Roles & Student Guidance Outcomes
1、Member of the Radiological Medicine and Protection Professional Committee of Jiangsu Provincial Preventive Medicine Association (2021.08-2026.08)
2、Member of the Editorial Board of BMC Cancer (2023.09-Present)
Ⅴ、Recent Five-Year Representative Research Outcomes
1. Ting Sun*, Bin Liu, Yufei Cao, Yanyan Li, Lize Cai, Wei Yang*. AMPK-mediated CD47 H3K4 methylation promotes phagocytosis evasion of glioma stem cells post-radiotherapy. Cancer Lett. 2024; 583: 216605.
2. Ting Sun*, Bin Liu, Yanyan Li, Jie Wu, Yufei Cao, Shuangyu Yang, Huiling Tan, Lize Cai, Shiqi Zhang, Xinyue Qi, Dingjia Yu, Wei Yang *. Oxamate enhances the efficacy of CAR-T therapy against glioblastoma via suppressing ectonucleotidases and CCR8 lactylation. J Exp Clin Cancer Res. 2023; 42(1): 253.
3. Ting Sun*, Yanyan Li, Ying Yang, Bin Liu, Yufei Cao, Wei Yang*. Enhanced radiation-induced immunogenic cell death activates chimeric antigen receptor T cells by targeting CD39 against glioblastoma. Cell Death Dis. 2022; 13(10): 875.
4. Ruoling Gao#, Yuan Gu#, Ying Yang, Yuping He, Wenpeng Huang, Ting Sun, Zaixiang Tang, Yong Wang*, Wei Yang*. Robust Radiosensitization of Hemoglobin-Curcumin Nanoparticles Suppresses Hypoxic Hepatocellular Carcinoma. Journal of Nanobiotechnology. 2022; 20(1): 115.
5.Wei Yang*, Yanyan Li, Ruoling Gao, Zenghe Xiu, Ting Sun*. MHC class I dysfunction of glioma stem cells escapes from CTL-mediated immune response via activation of Wnt/β-catenin signaling pathway. Oncogene. 2020; 39(5): 1098-1111.