Name: Hailong Pei
Academic Title: Professor
Email: hlpei@suda.edu.cn
Address: Medical Building 402-2222, North District of Dushu Lake Campus
Contact Phone: +86 512 65882451
Ⅰ、Educational and Professional Experience
1、Educational Background:
2010.09-2015.07 Institute of Modern Physics, Chinese Academy of Sciences, Ph.D. in Biophysics
2006.09-2010.07 Northwest University, Bachelor of Science
2、Professional Experience:
2025.07-present Professor, School of Radiation Medicine and Protection, Soochow University
2018.07-2025.07 Associate Professor, School of Radiation Medicine and Protection, Soochow University
2015.09-2018.07 Assistant Professor, School of Radiation Medicine and Protection, Soochow University
Ⅱ、Research Focus
1、Non-Coding RNA and Radiation-Induced Biological Effects
2、Regulation of Cytoskeletal Dynamics and Organelle Homeostasis
3、Functions of Small Proteins Translated from Non-Coding RNAs
Ⅲ、Project/Honor/Award
1、NSFC-General Program, Mechanistic Study of m6A Methylation-Regulated Micropeptides Translated by lncRNA AFAP1-AS1 in Mitophagy Inhibition-Mediated Radiation-Induced Pulmonary Fibrosis, 82273578, ￥520,000, 2023.01-2026.12.
2、NSFC-General Program, Mechanism of Radiation-Induced LNC CRYBG3 Targeting Bub3-Cdc20 Complex Leading to Spindle Assembly Checkpoint Escape, 82073480, ￥560,000, 2021.01-2024.12.
3、NSFC-Young Scientists Fund, LncRNA PHL13 Regulates Carbon Ion Irradiation-Induced Apoptosis by Targeting the Actin-PC4 Pathway, 81602794, ￥180,000, 2017.01-2019.12.
4、China Postdoctoral Science Foundation-Special Funding (10th Batch)-Application Value of LncRNA PHL13 in Inducing Cytoskeletal Collapse. 2017T100399, ￥150,000, 2027.01-2019.07.
5、Jiangsu Basic Research Program (Natural Science Foundation)-Young Scientists Fund- Role of LncRNA PHL13 in Carbon Ion-Induced Apoptosis via Targeting Cytoskeletal Proteins. BK20160334,2016.07-2019.06.
Ⅳ、Academic Part-time Roles & Student Guidance Outcomes
1、Member, Committee of Radiation Oncology, China Anti-Cancer Association
2、Young Member, Division of Radiation and Environmental Biophysics, China Biophysical Society
3、Member, Committee of Radiation Toxicology, Jiangsu Society of Toxicology
Ⅴ、Recent Five-Year Representative Research Outcomes
1、Yuhao Gong#, Wenxiao Shi#, Xingzhu Liu#, Hang Yu, Yinghui Wu, Yanzhang Xia, Caichun Yue, Chongkai Yang, Cong Shen, Renjun Pei, Tianwen Xin,* Hailong Pei,* and Jun Shen*. Brachyury-Activated Fucoidan Hydrogel Microspheres Rejuvenate Degenerative Intervertebral Discs Microenvironment. Advanced Science. 2025, e04195.
2、Hailong Pei*, Yingchu Dai, Yongduo Yu, Jiaxin Tang, Zhifei Cao, Yongsheng Zhang, Bingyan Li, Jing Nie, Tom K. Hei*, Guangming Zhou*, The tumorigenic effect of lncRNA AFAP1-AS1 is mediated by translated peptide ATMLP under the control of m6A methylation. Advanced Science. 2023, 2300314.
3、Hailong Pei#, Wentao Hu# , Ziyang Guo#, Huaiyuan Chen, Ji Ma, Weidong Mao, Bingyan Li, Aiqing Wang, Jianmei Wan, Jian Zhang, Jing Nie, Guangming Zhou*, and Tom K. Hei*. Long non-coding RNA CRYBG3 blocks cytokinesis by directly binding G-actin. Cancer Research. 2018, 78(16): 4563-4572.
4、Zeyin He#, Shiyi Gong#, Xu Zhang, Jie Li, Jinglin Xue, Qi Zeng, Jing Nie, Zengli Zhang, Hongmei Ding*, Hailong Pei*, Bingyan Li*. Activated PARP1/FAK/COL5A1 signaling facilitates the tumorigenesis of cholesterol-resistant ovarian cancer cells through promoting EMT. Cellular Signaling 2024 (124) 111419
5、Yingchu Dai#, Yongduo Yu#, Jing Nie, Ke Gu, Hailong Pei*. X-ray downregulated nucleophosmin induces abnormal polarization by anchoring to G-actin. Life Sciences in Space Research. 2023 (40), 81-88.
6、Wanshi Li#, Yongduo Yu#, Guangming Zhou, Guang Hu, Bingyan Li, Hong Ma, Wenying Yan*, Hailong Pei*. Large-scale ORF screening based on LC-MS to discover novel lncRNA-encoded peptides responding to ionizing radiation and microgravity. Computational and Structural Biotechnology Journal. 2023 (21), 5201-5211.
7、Jiaxin Tang#; Jiyuan Liu#; Jing Nie; Hailong Pei*; Guangming Zhou*, YBX1 Underwent Phase Separation into Stress Granules Stimulated by Ionizing Radiation. Radiation Research 2024, 201(3):215-223.
8、Jiyuan Liu, Guangming Zhou, Hailong Pei*. The clinical prospect of FLASH radiotherapy. Radiation Medicine and Protection. 2023, 4(4): 190-196.
9、Anqing Wu, Jiaxin Tang, Ziyang Guo, Yingchu Dai, Jing Nie, Wentao Hu, Ningang Liu; Caiyong Ye, Shihong Li, Hailong Pei*, Guangming Zhou*. Long Non-Coding RNA CRYBG3 Promotes Lung Cancer Metastasis via Activating the EF1A1/MDM2/MTBP Axis, International Journal Of Molecular Sciences, 2021, 22(6): 3211.
10、Anqing Wu, Jiaxin Tang, Yingchu Dai, Hao Huang, Jing Nie, Wentao Hu, Hailong Pei*, Guangming Zhou*. Downregulation of Long Noncoding RNA CRYBG3 Enhances Radiosensitivity in Non-Small Cell Lung Cancer Depending on p53 Status. Radiation Research, 2022, 198 (3), 297-305.