Name: Qiu Chen
Technical title: Professor
Email：happyqiu@suda.edu.cn
Office address: Medical Building 401-1331
Tel: 13771722172
I、Education and Work Experiences
1、Education Experiences
1999.9-2006.4 Zhejiang University, School of Life Science, Master/Ph.D degree of Science
1994.9-1998.7 Nankai University, School of Life Science, Bachelor of Science
2、Work Experiences
2017.1-Present Soochow University, School of Radiation Medicine and Protection, Professor
2009.1-2017.1 Soochow University, School of Radiation Medicine and Protection Associate Professor
2006.4-2009.1 Soochow University, School of Radiation Medicine and Protection, Lecturer
Ⅱ、Research Interests
1、The role and mechanism of immune cells in ionizing radiation-induced normal tissue damage and tumor radiotherapy
2、The role and mechanism of novel genes in ionizing radiation-induced normal tissue damage
3、The role and mechanism of drugs in ionizing radiation-induced normal tissue damage and tumor radiotherapy
Ⅲ、Projects
1、National Natural Science Foundation of China, General Project, 81773355, Mechanism study on recruitment of intestinal crypt stem cells and cooperation of lamina propria macrophages to repair radiation-induced intestinal injury, January 2018- December 2021, 600,000 Yuan, completed. Principal Investigator.
2、National Natural Science Foundation of China, General Project, 81372920, Study on the Mechanism of Yunzhi Polysaccharide in Preventing and Treating Small Intestinal Radiation Injury through TLR2/Akt Pathway, from January 2014- December 2017, 850,000 yuan, completed. Principal Investigator.
3、National Natural Science Foundation of China, Youth Project, 81001317, Molecular research involved in the signaling pathway of the new LPS inflammation negative regulatory molecule PDCD2like protein, from January 2011- December 2013, 200,000 yuan. Principal Investigator.
Ⅳ、Academic part-time jobs, guiding student achievements
Member, Jiangsu Society of Immunology Radioimmunology Special Committee 2020-2025
V、Representative research achievements in the past five years
1、Lu X, Xu Y, Liu Y, Li F, Feng Q, Gao C, Liu D, Zhou L, Yang H, Zhang J, Cui F, Chen Q. Neutrophil Depletion Reduced the Relative Abundance of Unsaturated Long-Chain Fatty Acid Synthesis Microbiota and Intestinal Lipid Absorption. Cell Biochem Funct. 2025, 43(3):e70060. doi: 10.1002/cbf.70060. PMID: 40016914
2、Wu Z, Xu L, Xu X, Hou J, Li W, Luo G, Xu Y, Chen Q, Cui F. Loureirin hydrogel promotes healing of radionuclide-contaminated wounds by regulating angiogenesis and immune cells. Biomater Sci. 2024, 12(22):5789-5802. doi: 10.1039/d4bm00813h. PMID: 39402942.
3、Duan N, Ran Y, Wang H, Luo Y, Gao Z, Lu X, Cui F, Chen Q, Xue B, Liu X. Mouse testicular macrophages can independently produce testosterone and are regulated by Cebpb. Biol Res. 2024, 57(1):64. doi: 10.1186/s40659-024-00544-8. PMCID: PMC11382419.
4、Zhang K, Wu Z, Zhao Y, Qiu X, Li F, Chen Q, Cui F. LC3 Accelerated Brain-Lung Axis Abscopal Effects after Fractionated Whole-Brain Radiation by Promoting Motoneurons to Secrete Periostin. Radiat Res. 2023, 200(5):462-473. doi: 10.1667/RADE-23-00075.1. PMID: 37796808.
5、Ran L, Chen Q, Lu X, Gao Z, Cui F, Liu X, Xue B. Novel treatment and insight for irradiation-induced injuries: Dibucaine ameliorates irradiation-induced testicular injury by inhibiting fatty acid oxidation in primary Leydig cells. Biomed Pharmacother. 2023, 164:114903. doi: 10.1016/j.biopha.2023.114903. 2023, 164:114903. PMID: 37224756.
6、Chen Q, Yao L, Liu Q, Hou J, Qiu X, Chen M, Wu Z, Hu D, Cui F, Yan T. Exosome-coated polydatin nanoparticles in the treatment of radiation-induced intestinal damage. Aging (Albany NY). 2023, 15(14):6905-6920. doi: 10.18632/aging.204882. PMCID: PMC10415572.
7、Tian XX, Liu YT, Li Y, Qiu XY, Zhang WH, Young DJ, Chen Q. ZIF-8 with cationic defects toward efficient 125I2 uptake for in vitro radiotherapy of colon cancer. Chem Commun(Camb). 2022, 58(49):6942-6945. doi: 10.1039/d1cc07304d. PMID: 35640157.
8、Yan HB, Liu YT, Li ZY, Wu ZJ, Zhang M, Xue PJ, Liu YL, Wang KZ, He YM, Tu Y, Cui FM, Chen Q. Tritiated Water Induces Toxicity in Human Umbilical Vein Vascular Endothelial Cells via IL8. Dose Response. 2020, 18(3):1559325820938541.