Name: Ming Li
Academic Title: Associate Professor
Email: lim1984@suda.edu.cn
Address: Medical Building 402-2303, North District of Dushu Lake Campus
Contact Phone: +86 18862392675
Ⅰ、Educational and Professional Experience
1、Educational Background：
2005.9-2010.7 Beijing Institute of Radiation Medicine, Ph.D. in Radiation medicine
2001.9-2005.7 Inner Mongolia Agricultural University, College of life sciences, B.E. in Bioengineering
2、Professional Experience：
2010.8-2018.6 Soochow University, School of Radiation Medicine and Protection, Lecturer,
2018.7-present Soochow University, School of Radiation Medicine and Protection, Associate Professor
Ⅱ、Research Focus
1、Mechanism and treatment of radiation-induced intestinal injury
2、Radiosensitization of digestive tract tumors
3、Research damage and protection from space radiation
Ⅲ、Project/Honor/Award
1、NSFC, Effects and mechanisms of mitochondrial dynamic equilibrium in regulating ferroptosis of intestinal stem cells during radiation-induced intestinal injury, 82473578, ￥490,000, 2025.01-2028.12。
2、NSFC, Research on the Mechanism of PIG3-DNA PKcs Signaling Pathway Regulating Ionizing Radiation Induced Mitotic Catastrophe, 81673091, ￥550,000, 2017.01-2020.12。
3、NSFC, The role and mechanism of KLF5 in radiation-induced intestinal injury, 31300694, ￥220,000, 2014.01-2016.12。
4、Ye Tian, Ming Li, Shang Cai, Qi Guo, Pei-Feng Zhao, Jia-Ying Xu, Qi-Liang Peng, Jian-Jun Qian, Yan-Ze Sun. Research and application of new technology for diagnosis and treatment of intestinal radiation injury. Second Prize of National Defense Science and Technology Progress Award. 2024
5、Ye Tian, Ming Li, Shang Cai, Qi Guo, Pei-Feng Zhao, Jian-Jun Qian, Qi-Liang Peng. Research and application of new technology for diagnosis and treatment of radiation-induced intestinal injury. Third Prize of Jiangsu Medical Science and Technology Award. 2023
Ⅳ、Academic Part-time Roles & Student Guidance Outcomes
·Youth Editorial Board Member of Radiation Medicine and Protection.
·Member of the Radiation Medicine and Protection Professional Committee of Jiangsu Preventive Medicine Association.
·Member of the Second Committee of the Basic and Translational Medicine Branch of the Chinese Geriatric Society.
·Mentorship to two master's degree students recognized for Excellent Master Theses from Soochow University.
·Assist in guiding master's and doctoral students in obtaining national scholarships, outstanding graduate students, and other honorary titles.
Ⅴ、Recent Five-Year Representative Research Outcomes
1、Tang LF*, Tang FL*, Zhou H*, Li ZK, Pi CQ, He Y#, Li M#. Bacillus Coagulans BC99 Protects Ionizing Radiation-Induced Intestinal Injury and Modulates Gut Microbiota and Metabolites in Mice. Mol Nutr Food Res. 2025;69(11):e70057.
2、Xie LW*, Cai S*, Lu HY, Tang FL, Zhu RQ, Tian Y#, Li M#. Microbiota-derived I3A protects the intestine against radiation injury by activating AhR/IL-10/Wnt signaling and enhancing the abundance of probiotics. Gut Microbes. 2024; 16(1): 2347722.
3、Xie LW*, Lu HY*, Tang LF*, Tang FL, Zhu RQ, Wang DF, Cai S, Tian Y#, Li M#. Probiotic Consortia Protect the Intestine Against Radiation Injury by Improving Intestinal Epithelial Homeostasis.Int J Radiat Oncol. 2024;120(1):189-204.
4、Lu H*, Xie L*, Guo L*, Gu X, Zhu R, Yang Y, Tang F, Li M, Liu C, Wang D, Li M#, Tian Y#, Cai S#. EGCG protects intestines of mice and pelvic cancer patients against radiation injury via the gut microbiota/D-tagatose/AMPK axis. Radiother Oncol. 2024;202:110608.
5、Tang FL*, Xie LW*, Tang LF*, Lu HY, Zhu RQ, Wang DF, Tian Y#, Cai S#, Li M#. Fraxin (7-hydroxy-6-methoxycoumarin 8-glucoside) confers protection against ionizing radiation-induced intestinal epithelial injury in vitro and in vivo. Int Immunopharmacol. 2024; 129: 111637.
6、Xu J*, He J*, Zhou YL, Weng Z, Li M#, Wang ZX#, He Y#. Von Willebrand factor promotes radiation-induced intestinal injury (RIII) development and its cleavage enzyme rhADAMTS13 protects against RIII by reducing inflammation and oxidative stress. Free Radic Biol Med. 2024; 210: 1-12.
7、Tang LF*, Ma X*, Xie LW*, Zhou H, Yu J, Wang ZX#, Li M#. Perillaldehyde Mitigates Ionizing Radiation-Induced Intestinal Injury by Inhibiting Ferroptosis via the Nrf2 Signaling Pathway. Mol Nutr Food Res. 2023; 67(19): e2300232.
8、Zhou H*, Zhou YL*, Mao JA*, Tang LF, Xu J, Wang ZX#, He Y#, Li M#. NCOA4-mediated ferritinophagy is involved in ionizing radiation-induced ferroptosis of intestinal epithelial cells. Redox Biol. 2022 Jul 30;55:102413.
9、Cai S*, Xie LW*, Xu JY*, Zhou H, Yang C, Tang LF, Tian Y#, Li M#. (-)-Epigallocatechin-3-Gallate (EGCG) Modulates the Composition of the Gut Microbiota to Protect Against Radiation-Induced Intestinal Injury in Mice. Front Oncol. 2022 Apr 11;12:848107.
10、Zhao TS*, Xie LW*, Cai S*, Xu JY, Zhou H, Tang LF, Yang C, Fang S, Li M#, Tian Y#. Dysbiosis of Gut Microbiota Is Associated With the Progression of Radiation-Induced Intestinal Injury and Is Alleviated by Oral Compound Probiotics in Mouse Model. Front Cell Infect Microbiol. 2021; 11: 717636.