Name: Jia-Ying Xu
Academic Title: Research Fellow
Position: Office Director
Email: xujiaying@suda.edu.cn
Address: Medical Building 402-A303, North District of Dushu Lake Campus
Contact Phone: +86 512 65880050
Ⅰ、Educational and Professional Experience
1、Educational Background：
2009.09 - 2013.12 Soochow University, China, Ph.D
2003.03 - 2005.04 Yamanashi University, Japan, M.S.
1991.09 - 1994.07 Nanjing Medical University, China, M.D.
2、Professional Experience：
2005.05-Present School of Radiation Medicine and Protection, Medical College of Soochow University
2003.04-2005.03 Department of Obstetrics and Gynecology, University of Yamanashi, Japan
2000.11-2003.03 Department of Environmental Health, University of Yamanashi, Japan
1994.08-2000.11 Jianhu No.2 Hospital, Jiangsu Province, China
Ⅱ、Research Focus
1. Prevention of Radiation Injury
2. Nutritional Interventions in Tumors and Radiation Injury
3. Biological Effects and Mechanisms of FLASH
Ⅲ、Project/Honor/Award
1. NSFC, Lactoferrin Improves Radiation-Induced Intestinal Injury by Regulating Hypoxic Microenvironment, 82073482, ￥660,000, 2021.01 - 2024.12. Principal Investigator
2. JNMRP, Sanguinarine prevents radiation-induced intestinal injury by regulating the NF-κB inflammatory pathway and reshaping the intestinal microbiota, 18KJA310006, ￥300,000, 2018.09 - 2021.08 Principal Investigator
3. NSFC, Protective Effects and Mechanism of Metformin on Radiation-Induced Lung Injury, 81673101, ￥540,000, 2017.01 - 2020.12 Principal Investigator
4. NKRDP, Research on the Large-scale Preparation and Clinical Transformation of Novel Nano-sized Iron Oxide Magnetic Resonance Contrast Agents, 2018YFA0208800, Sub-project Funding,￥2.547 million , 2018.07-2020.12 Co-investigator
Ⅴ、Recent Five-Year Representative Research Outcomes
1. Qing Li#, Jia Shi#, Xiaokang Ruan, Rui Fu, Liqiang Qin, Jiaying Xu*, Yu Chong*, Chunhong Hu*. Hypoxia- and pH-Responsive Metal-Phenolic Network-Engineered Ferroptosis-Immuno Microspheres for Transarterial Chemoembolization in Hepatocellular Carcinoma. Advanced Functional Materials.2025, e10798.
2. Yu-Zhong Chen#, Lin Zhao#, Wei Wei#, Jia Gu, Zhen-Hua Liu, Wen-Yue Shan, Jie Dong, Chao Li, liqiang qin, Jiaying Xu*. The Effect of Metformin on Radiation-induced Lung Fibrosis in Mice. Dose Response. 2024, 22(4):15593258241308051.
3. LiLi Zhang, Jia-Ying Xu*, Wei Wei, Zhi-Qiang Hu, Yan Zhou, Jia-Yang Zheng, Yu Sha, Lin Zhao, Jing Yang, Qi Sun, Li-Qiang Qin*. Dietary restriction and fasting alleviates radiation-induced intestinal injury by inhibiting cGAS/STING activation. Journal of Nutritional Biochemistry. 2024, 133:109707.
4. Jia Yang Zheng#, Jia Ying Xu#, Lin Zhang, Zhang Min Wang, Xue Bin Yin, Li Qiang Qin*. Effect of 3,3'-diselenodipropionic Acid on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice. Biological Trace Element Research 2023, 201(8):3961-3970.
5. Yun-Hong Li, Jiang-Xue Wu, Qian He, Jia Gu, Lin Zhang, Hao-Zhi Niu, Xin-Wen Zhang, Han-Ting Zhao, Jia-Ying Xu*, Li-Qiang Qin*. Amelioration of radiation-induced liver injury by p-coumaric acid in mice. Food Sci Biotechnol. 2022, 31(10):1315-1323.
6. Jia Gu#; Lin Zhao#; Yu-Zhong Chen#; Ya-Xin Guo; Yue Sun; Guang-Xin Duan; Zhi-Bing Tang; Zhi-Xiang Zhang; Li-Qiang Qin*; Jia-Ying Xu*. Amelioration of Intestinal Injury Induced by Whole Abdominal Irradiation in Mice by Sanguinarine. Biomedicine & Pharmacotherapy. 2022, 146:112496.
7. Yuzhong Chen#, Chao Li#, jia Gu, Zhibing Tang, Sichen Lv, Jiaying Song, Guangxin Duan, Liqiang Qin, lin zhao* and Jia-Ying Xu*. Anti-oxidative and immuno-protective effect of camel milk on radiation-induced C57BL/6 J intestinal injury in mice. Dose Response.2021, 19(1):15593258211003798.
8. Yun-Hong Li, Qian He, Yu-Zhong Chen, Ya-Fang Du, Ya-Xin Guo, Jia-Ying Xu*, Li-Qiang Qin*. p-Coumaric acid ameliorates ionizing radiation-induced intestinal injury through modulation of oxidative stress and pyroptosis. Life Sci. 2021, 278:119546.
9. Jia Gu#,Yu-Zhong Chen#, Qing Guo, Zai_Xing Yang, Guang-Xin Duan, Li-Qiang Qin, Lin Zhao*,Jia-Ying Xu*. How much doses of total-body and whole abdominal irradiation cause lethal intestinal injury in C57BL/6 mice. Dose Response. 2020, 18(3):1559325820956783.
10. Lianxue Zhang#, Shitong Zhang #, Jiaying Xu#, Youyun Li, Jinlin He,; Ying Yang, Huynh, Tien; Peihong Ni, Guangxin Duan, Zaixing Yang*, Ruhong Zhou*. Low-dose X-ray Responsive Diselenide Nanocarriers for Effective Delivery of Anticancer Agents. ACS Appl Mater Interfaces. 2020, 12(39):43398-43407.