Name: Yu Jiahua
Academic Title: Associate Professor
Email: yujiahua@suda.edu.cn
Address: Medical Building 402-2303, North District of Dushu Lake Campus
Contact Phone: +86 13913540349
Ⅰ、Educational and Professional Experience
1、Educational Background：
2008.03-2010.02 Chonbuk National University (Korea), Medical School, PhD
2006.09-2008.02 Chonbuk National University (Korea), Medical School, MD
1999.09-2004.06 Soochow University, School of Radiation Medicine and Protection, bachelor
2、Professional Experience：
2013.07-Present Soochow University, School of Radiation Medicine and Protection, Associate Professor
2011.03-2013.07 Soochow University, School of Radiation Medicine and Protection, Lecturer
2010.03-2011.02 Chonbuk National University (Korea), Medical School, Postdoctoral Fellow
Ⅱ、Research Focus
1、DNA damage and repair
2、Genetic mutation induced by ionizing radiation
Ⅲ、Project/Honor/Award
1、NSFC, The genomic mutational spectra decomposition and signature profiling in ionizing radiation-treated Saccharomyces cerevisiae, 82273583, ￥520,000, 2023.01-2026.12。Role: P.I.
2、NSFC, CRISPR/Cas9-based screening for HR and NHEJ repair genes and the functional study on their regulation of radiosensitivity, 81872548, ￥520,000, 2019.01-2022.12。Role: P.I.
3、NSFC, Study on Adipose-Derived Stem Cell Therapy for Radiation-Induced Lung Injury and Its Mechanisms, 81202149, ￥230,000, 2013.01-2015.12。Role: P.I.
4、Second Prize of Jiangsu Provincial Teaching Achievement Award, Research and Practice on a Collaborative Integration Model of Medical-Education-Research for Cultivating Excellence in Radiation Medicine Talent Development, 2022.03。
5、Jiangsu Higher Education Teaching Reform Research Approved Project, Construction and Practice of a New Paradigm of Science-Education Integration for Cultivating Top-notch Innovative Talents in Radiation Medicine, 2023.01-2025.12。
Ⅳ、Academic Part-time Roles & Student Guidance Outcomes
Member of the Youth Committee, Environment and Radiation Biophysics Branch, Chinese Biophysical Society. 2022-2026
Council Member, Medical Physics Branch, Chinese Nuclear Society 2023-2028
Youth Editorial Board Member, Journal of Radiation Research and Radiation Processing 2022-2026
Council Member, China Nuclear Industry Education Society 2025-2030
Ⅴ、Recent Five-Year Representative Research Outcomes
1、Wang Ting，Yu Sutong，Li Jie，Guo Yihan，Yu Jiahua. Research progress on the ionizing radiation-induced mutational signatures. Chinese Journal of Radiological Medicine and Protection, 2024, 44(7): 628-632.
2. Jie Du, Fuqiang Chen, Jiahua Yu, Lijun Jiang, Meijuan Zhou. The PI3K/mTOR inhibitor ompalisib suppresses nonhomologous end joining and sensitizes cancer cells to radio- and chemotherapy. Molecular Cancer Research. 2021, 19(11):1889-1899.
3. Chen Jinhua, Huang Xiaoting, Jin Jiaying, Ding Boyang, Zhu Ran, Li Wenyan, Liu Fenju, Yu Jiahua.Construction and application of a random forest-based classification model for DNA double-strand break induced by ionizing radiation. Chinese Journal of Radiological Medicine and Protection, 2021, 41(6): 413-417.
4. Jie Du, Narui Yin, Ting Xie, Yunfeng Zheng, Ning Xia, Jun Shang, Fei Chen, Haowen Zhang, Jiahua Yu, Fenju Liu. Quantitative assessment of HR and NHEJ activities via CRISPR/Cas9-induced oligodeoxynucleotide-mediated DSB repair. DNA Repair (Amst). 2018, 70:67-71.
5. Jie Du, Jun Shang, Fei Chen, Shuyu Zhang, Narui Yin, Ting Xie, Haowen Zhang, Jiahua Yu, Fenju Liu. A CRISPR/Cas9-based screening for non-homologous end joining inhibitors reveals ouabain and penfluridol as radiosensitizers. Mol Cancer Ther. 2018, 17(2):419-431.